On the rugged isle of Berk, where Vikings and dragons have been bitter enemies for generations, Hiccup stands apart, defying centuries of tradition when he befriends Toothless, a feared Night Fury dragon. Their unlikely bond reveals the true nature of dragons, challenging the very foundations of Viking society.

A group of survivors of the rage virus lives on a small island. When one of the group leaves the island on a mission into the mainland, he discovers secrets, wonders, and horrors that have mutated not only the infected but other survivors.